Aptamer Group's H1 2026: 27% revenue growth, first licensing payments in, and strategic push into radiopharma with new fundraise.
This article covers information on Aptamer Group PLC.
LON:APTAAptamer Group has posted a steadier, more commercially focused half-year for the six months to 31 December 2025. Revenue grew 27% to £0.83 million as pharma customers came back for more, losses edged lower, and – critically – the first product-linked licensing payments have started to land post period. With a new fundraise launched to bring in at least £3.75 million, the company is pushing harder on asset development while keeping a lean cost base.
In plain English: more work delivered, better customer traction, and early proof that the licensing model is real, albeit still small today.
| Metric | H1 2026 | H1 2025 | Why it matters |
|---|---|---|---|
| Revenue | £0.83 million | £0.65 million | +27% year-on-year as fee-for-service work scales |
| Gross margin | 56% | 56% | Stable margins while growing delivery |
| Adjusted EBITDA loss | £1.0 million | £1.1 million | Loss narrowing on higher revenue and cost discipline |
| Loss after tax | £1.1 million | £1.1 million | Still loss-making, but broadly flat despite business investment |
| Cash balance | £1.5 million | £2.0 million | Runway guided to Q2 2027 on current trajectory pre-raise |
| Orders in progress | £1.2 million | Not disclosed | Near-term revenue visibility, subject to scientific attrition |
| Pipeline at period end | £3.1 million | Not disclosed | Conversion here would underpin H2 momentum |
Fee-for-service means customers pay Aptamer to discover and develop “Optimer” binders for their targets. This work creates data, relationships and – increasingly – licensable assets that can earn royalties and supply revenue later. That flywheel is starting to turn.
Geographically, Rest of World carried the load at £660,000, with the UK at £150,000 and Europe a modest £18,000. The customer mix should keep gross margins healthy so long as lab utilisation stays high.
Licensing is where the long-term economics kick in. Aptamer out-licensed enzyme-modulating Optimers to Twist Bioscience and Alphazyme. The terms include upfront cash, royalties and supply revenue. Post period, both partners launched Optimer-containing kits and Aptamer received the first licensing payments – small today, but strategically important.
A crucial enabler here is supply. Aptamer has expanded manufacturing capacity and completed quality audits to support partner-grade production. That should protect margins and reduce friction as the licensed portfolio grows.
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The Unilever collaboration continues to move through development gates. Stability work on the first deodorant programme is done and supports ongoing on-skin testing. A second odour-prevention programme has delivered positive internal results and is approaching customer evaluation. If licensed, this could open a broad consumer channel.
In therapeutics, the fibrotic liver delivery vehicle showed excellent preclinical characteristics – non-toxic, stable and non-immunogenic – which materially de-risks the concept. Animal studies are anticipated to begin this financial year to demonstrate targeting and safety, with applications across multiple fibrotic diseases.
Radiopharma is being doubled down on. Beyond the big-pharma development contract, Aptamer initiated an internal radiotherapeutic programme with three targets, adding to one partnered asset for a total of four. Preclinical results from the Radiopharmium partnership are anticipated by the end of 2026. Manufacturing and preclinical work will be overseen by a radiopharma expert on the company’s Scientific Advisory Board.
An Accelerated Book Build (ABB) is a quick-fire institutional placing. Aptamer launched one on 25 March 2026 to raise at least £3.75 million gross. Management says proceeds will extend the cash runway through to 2028 and fund both new and existing assets, plus AI-enhanced fee-for-service capabilities.
Pre-raise, cash was £1.5 million at 31 December 2025, with guidance of runway through to Q2 2027 on the expected trajectory, assuming licensing revenues start to scale. The raise does mean dilution – the detailed terms beyond the minimum gross amount are not disclosed here – but it buys time to convert today’s evaluations into recurring royalties.
This is a better-quality half for Aptamer. Revenues are growing, margins are steady, and there is now hard evidence that the licensing route can pay. The mix of near-term service income and longer-term royalties is taking shape, with manufacturing and quality groundwork laid to support scale.
Against that, the base is still small, losses persist, and the business remains reliant on timely conversion of contracts and continued access to equity capital. The ABB is sensible if it accelerates asset development and bridges to meaningful royalty scale.
For retail investors, the story is improving but still execution-heavy. If Aptamer can turn today’s evaluations into multiple licensing deals – while landing the Unilever and IHC opportunities – the revenue profile should look very different over the next 12 to 24 months. Until then, expect the shares to be news driven by contract closures, licensing completions and early therapeutic readouts.
Management will present the Interim Results on Monday, 30 March 2026 at 14:00 GMT via Investor Meet Company. Existing and potential shareholders can submit questions during the live session.
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